The Dublin-born writer is on a shortlist of six for the Orange Prize for Fiction for her fifth novel, The Forgotten Waltz.
Enright won the Man Booker in 2007 for The Gathering and has been nominated three times for the Orange Prize.
“This is a shortlist of remarkable quality and variety,” said Joanne Trollope, the chair of the prize.
“It includes six distinctive voices and subjects, four nationalities and an age range of close on half a century. It is a privilege to present it.”
The shortlist is completed by Half Blood Blues by Esi Edugyan, Painter of Silence by Georgina Harding, The Song of Achilles by Madeline Miller, Foreign Bodies by Cynthia Ozick, and State of Wonder by Ann Patchett.
The £30,000 (€36,000) Orange Prize was set up in 1996 to celebrate and promote fiction by women. The award ceremony will take place in London on May 30.