Is 'microdosing' weight-loss drugs safe? Here's what the experts say

Ozempic and similar GLP-1 drugs are at the forefront of helping to control type 2 diabetes and obesity. But what about their effect, when taken in microdoses, on those who are struggling to shed additional weight?

Dr Michael Crotty: Microdosing is not a medical term.

Anna* (54) has been microdosing a GLP-1 for two years. She has shed 18% of her weight and her body mass index has shifted from the ‘overweight’ to the ‘healthy weight’ category.

“I was carrying a lot of extra weight for my frame and nothing I tried shifted it,” she says. “I went to a personal trainer twice a week for two years, improved my diet, got in plenty of daily steps, but the number on the scales just kept creeping up. My joints were stiff and painful sometimes and, to be perfectly honest, the way I looked was really affecting my mental health.