Dietmar Hamann will miss both legs of Liverpool’s Champions League quarter-final against Juventus after being ruled out of action for a month.
The German midfielder left the field after sustaining knee ligament damage during Sunday’s Merseyside derby victory over Everton at Anfield.
Hamann had been due to link up with the Germany squad this week but is now unlikely to train again until the end of April.
Manager Rafael Benitez, whose side return to action against Bolton on April 2, told the club’s official website, www.liverpoolfc.tv: “Didi will be out for a month.
“He has a ligament problem and usually it takes at least four weeks to recover.
“Now we need to look at some of the youngsters who did so well in the Carling Cup.
“I’d prefer not to talk too much about my options for the Bolton game now because of the internationals.
“I can plan to use players, but I have to make sure they come back from their national team fit.
“I need to wait and keep my fingers crossed. If I say I want to play with Luis Garcia and Steven Gerrard as attackers, I may find both are unavailable. After all, I now have a book of injuries.”
Luis Garcia, Stephen Warnock and Fernando Morientes were also hurt against the Toffees and Xabi Alonso remains a fortnight away from a return.
In Hamann’s absence Igor Biscan is likely to fill in for the Barclays Premiership games against Bolton, Manchester City and Tottenham as well as the two matches against Juve.
Biscan, however, has admitted he may be leaving Anfield in the summer.
The Croatian midfielder, signed by Gerard Houllier five years ago, considered moving on before Christmas but decided to stay to fight for his place.
He has been rewarded with a regular run in the side, including an appearance in the Carling Cup final, but has not established himself as a first choice.
“The way things are looking now I think I’ll be leaving at the end of the season,” the 26-year-old said.
“I want to do well for myself over the rest of the season and in doing so I’ll do well for the team.
“If I’m going to leave the club then it’s important I play games to show the other teams what I am capable of.”