Spanish-based striker Achille Webo netted with a brilliant diving header three minutes from time, reacting first as a long-range free kick cannoned back off the upright to take his country top of the African zone Group Three standings.
The goal completed a hat-trick for the striker whose efforts in front of goal had kept the home team on the back foot throughout the match as he traded goals with Chelsea’s Ivorian forward Didier Drogba.
Cameroon will now qualify for the World Cup finals in Germany if they win their final qualifier at home to Egypt in Yaounde on October 9.
The Ivory Coast will now only qualify if the beat Sudan away on October 7 and Cameroon slip up in their final qualifier.
Meanwhile early goals from Chelsea’s Michael Essien and Matthew Amoah earned Ghana a comfortable 2-0 win over Uganda in Kumasi and put them one point away from their first World Cup finals appearance.
Ghana moved three points clear at the top of the African zone group two standings and can now only be caught by the Democratic Republic of Congo, who were 2-1 home winners over the Cape Verde Islands.
However, it would take a major swing in goal difference on the last day of qualifiers on October 8 to deny Ghana’s Black Stars a place at next year’s finals in Germany.