Jeremy Noseda's Formosina broke the extraordinary stranglehold of Aidan O'Brien in the Ladbrokes.com Railway Stakes at the Curragh.
O'Brien had won the previous five runnings of the Group Two race and struck 11 times in all through the likes of George Washington and Rock Of Gibraltar, accounting for Samuel Morse being sent off the 5-2 favourite.
Samuel Morse did absolutely nothing wrong here as he jostled for the lead with Clondinnery, but he was unable to contain the late charge of Formosina (7-2) and Ryan Moore and had to surrender by just a short-head. Clondinnery was a further neck behind.
Formosina finished third to the Coventry Stakes winner Strong Suit on his debut before streaking clear at Doncaster, and this success came as no surprise to Noseda.
"He was travelling well and it was just a question of whether Ryan would get the run, but he picked up well," said the Newmarket trainer.
"I was happy with him at Newbury - he was behind possibly the best two-year-old we have seen this season - and he has improved.
"I thought of this race so I watched the Irish two-year-olds at Royal Ascot, and I thought he deserved the chance.
"I am sure he will get seven furlongs and I had the Vintage Stakes at Goodwood in my mind before this."
Victor Chandler gave the winner a 25-1 quote for next year's 2000 Guineas, with Paddy Power going 20s.
Johnny Murtagh had a very lucky escape in the opener when Petronius Maximus was involved in a freak incident.
Murtagh was still travelling well in the Dubai Duty Free Full Of Surprises EBF Maiden when his mount suddenly seemed to lose his action and crashed into the rails.
But Petronius Maximus (5-4 favourite) got up and cantered away while Murtagh managed to rise to his feet and walked back to the weighing room with O'Brien.
They had been challenging Michael Cleere on Sydney Harbour (4-1), who were left alone and finished two lengths clear.
Winning trainer David Wachman said: "Michael thought he had Johnny covered - as he would!
"He's a grand little horse and he could run in all those Group races - he's well entered-up. He just didn't get enough cover the last day."
Murtagh showed he had suffered no ill-effects when making all on O'Brien's Emperor Claudius (2-1 favourite) to hold Gold Bubbles in the Woodies D.I.Y Celebration Stakes.
British sprinters tend to have the edge over their Irish rivals and overseas raiders filled the first five places in the Dubai Duty Free Sapphire Stakes.
The winner Glamorous Spirit (16-1), who was punched home half a length clear of Reverence, brought about several landmarks for Welsh trainer Ron Harris, who had also saddled the unplaced Judge 'N Jury.
Next home were Elnawin, Piccadilly Filly and Spin Cycle.
"That's my first Group winner and my first winner in Ireland," revealed Harris.
"She's a very quick filly - she'd be unbeatable if there were races over four and a half furlongs.
"This is down to the owners, who own both horses. Glamorous Spirit was going to run in a Listed race at Chester in two weeks and Judge 'N Jury was coming here, but the ground went against Judge 'N Jury and the owner said we should run them both.
"She'll still run at Chester, the track would suit her better."
There was further British cheer in the Dubai Duty Free Double Millionaire Handicap through Sea Lord (4-1).
Frankie Dettori rode his rivals to sleep with a stop-start pace and had too many guns for Scandal Sheet.
Trainer Mark Johnston said: "He won twice and went to Royal Ascot, where he never really got a run and was boxed-in. He showed today what he can do from the front."
Invincible Ash stormed up the stands rail to claim the National Lottery Sweepstakes Race (Premier Handicap).
The Michael Halford-trained five-year-old was an armchair ride for Gary Carroll, coming right away for a five-length victory over the aptly-named Brushed Aside.
Hawkeyethenoo, the 5-2 favourite, was third with fellow British raider Novellen Lad fourth.
Halford said: "Six furlongs is probably her trip and we'll look for a Group Three for her."