The John Oxx-trained three-year-old was due to run in the Derrinstown Stud Derby Trial Stakes at Leopardstown on Sunday, but has suffered a strained hock.
Akeed Mofeed will instead be prepared for the Irish 2,000 Guineas in two weeks’ time followed by the Irish Derby at the Curragh.
“He’s got a problem with his hock,” said Bruce Raymond, racing manager to owner Jaber Abdullah.
“It’s not much of a problem but he couldn’t medicate it because it’s so close to the race. “John (Oxx) said he’d rather not go for the Derrinstown, and he’s not going to go for the Derby at Epsom without a prep race.
“His new programme will be the Irish Guineas and Irish Derby. The problem he had before when he missed his previous race was in front.
“This time he strained a hock when he worked well on Tuesday. It’s one of those unfortunate things.
“John waited until Friday to make up his mind and he wasn’t 100% happy with him.”
Bonfire meanwhile heads 12 confirmed for the Betfred Dante Stakes at York on Thursday. Andrew Balding’s highly-promising colt looks like being rerouted to the Knavesmire if conditions are suitable.
He was a late withdrawal from yesterday’s Dee Stakes due to the rain-softened ground at Chester.
York’s Group Two contest over an extended mile and a quarter is likely to be a significant trial for the Investec Derby at Epsom – even though it is just 16 days before the premier Classic on June 2.
Roger Varian has indicated Ektihaam, a convincing winner at Newbury last month, will run on the Knavesmire.
Aidan O’Brien has left in just two of his entries – the once-raced facile Dundalk winner Ernest Hemingway and Wrote. The latter, however, has been declared for the Derrinstown Stud Trial at Leopardstown on Sunday.
Henry Cecil has left in Frankel’s full brother Noble Mission, who has won both of his starts so far.