Rory Kavanagh and Kevin Rafferty are set to train with the Donegal squad tonight as they bid to prove their fitness ahead of Sunday's Ulster SFC final.
The midfield duo, who have been paired together in the recent wins over Cavan and Tyrone, both aggravated injuries in club action last week.
Kavanagh has an ankle injury, while his St Eunan's club-mate Rafferty is working his way back from a groin strain.
Donegal manager Jim McGuinness told RTÉ Radio 1: "The lads haven't managed to train with us since the club Championship last Sunday week.
"We train (on Thursday) so we'll have to wait and see what the fellas can do then. At that stage, we'll make a decision based on the medical evidence available.
"It's hard to know (if they'll make it). We're just dependent on the players themselves and the medical team. Obviously they're in a race against time."
McGuinness is definitely without the services of defender Leo McLoone who suffered a double fracture of his eye socket in a club game earlier this month.
Donegal's final opponents Derry are expected to announce their team tonight. Their manager John Brennan has played down the absence of sharpshooter Eoin Bradley.
The Glenullin clubman, Derry's top scorer in the 2011 Championship with 2-9 in two outings, injured his cruciate knee ligament last Sunday.
"I am not going to complain - we will manage our way through this," Brennan told the Irish Daily Mirror.
"We had plans in place, yes, but it's not hard to change one (player). We have a strong panel.
"If we feel sorry for ourselves, no one else will. I'm sorry for Eoin on a personal level, but I cannot concentrate on one player who can't be with us.
"I have to look after the fully fit players who are there. I treat everyone the same. If this had happened to someone on the fringes of the team, we would be feeling the same."