Pittsburgh is a city transformed and on the rise. Yet it still finds time to reflect on its fascinating history, writes Joe Leogue.

The New York Yankees have set a new record for the most home runs hit at an opposing team’s ballpark in a season, smashing five homers in a 9-6 win over the Baltimore Orioles to take their 2019 total at Camden Yards to 32.

Pfizer is buying Mylan in an all-stock deal and combining the $10bn generic pharmaceutical company with its own off-patent branded and generic business.

Ahead of US President Donald Trump's visit to Ireland this week, we asked a broad range of individuals and organisations to compose open letters explaining why he was or wasn't welcome to this country.

An American telecommunications services company is to create 200 new jobs in Waterford and Sligo over the next three years.

When Rabbi Yisroel Goldstein was released from a Californian hospital on Sunday, he said it was a miracle he was not dead and that “senseless hate” killings provoked by religious differences must stop.

US-born composer James May will have his prize-winning work performed at Cork International Choral Festival, writes

A shooting at a synagogue in the US has left people injured but the extent is unclear, according to authorities in southern California.

The electorate has the chance to break the Republicans’ lock on government in possibly the most consequential midterm elections in US history, writes Elizabeth Drew AHEAD of this week’s US midterm elections, domestic

Your lunchtime headlines.

“I’ll see you when I’m done.”

Young Irish scientists are heading for the stars as one is to have an asteroid named after him and six others are about to present a project to leading space engineers.

A domestic dispute spurred the shooting deaths of five people at a Pennsylvania car wash, family sources said.

Pope Francis will visit Ireland in 2018. Whether he will venture into the North isn’t yet known but, later in the year, Belfast will welcome another distinguished visitor.

Child protective agencies are haunted when they fail to save children. Officials in the US believe

Driving home for Christmas can do strange things to strange and not-so-strange people. The mind, as Paradise Lost told us, is its own place — it can make a heaven of hell or a hell of heaven. The journey for some may be filled with unbridled joy and excitement, anticipating long overdue reunions. F

A sudden power outage brought the world's busiest airport to a standstill on Sunday, grounding more than 1,000 flights in Atlanta just days before the start of the Christmas travel rush.

Everyone is mad at Google and CEO Sundar Pichai has to fix it. Mark Bergen and Brad Stone report

Uber plans to buy up to 24,000 self-driving cars from Volvo, marking the transition of the US firm from an app used to summon a taxi to the owner and operator of a fleet of cars.

He allegedly urged his lover to have an abortion when he thought she was pregnant.

A judge has agreed to delay the start of Bill Cosby's sexual assault retrial to allow his new lawyers to get up to speed on the case.

Whether visiting the Warhol Museum or going to a baseball game, you will never be short of something to do in Pittsburgh, says Michelle Darmody

French President Emmanuel Macron said it is "obvious and indispensable" to have exchanges with US President Donald Trump as the two leaders were set to try to find common ground on security, defence and other issues.

Increasing competition for the long-haul, low-cost transatlantic market will be a boon for passengers as airlines tussle for a share of the market, a leading aviation analyst has said, writes Padraig Hoare.

Increasing competition for the long-haul, low-cost transatlantic market will be a boon for passengers as airlines tussle for a share of the market, a leading aviation analyst has said.

A new business aims to integrate computer technology into our brains. But is this mix of humanity with technology desirable or ethical, ask Agata Sagan and Peter Singer.

Cork Airport is heralding a new era in transatlantic travel thanks to Wow Air’s new direct service to Iceland.

Passengers on Norwegian Airline’s new low-fares transatlantic flights from Ireland will be able to avail of US preclearance facilities at Dublin and Shannon airports. But Cork Airport said its lack of such facilities shouldn’t be an issue.

Bill Cosby has also suggested racism "could be" behind the scores of accusations against him.

Uber has said its self-driving cars remain suspended in Arizona and Pittsburgh, Pennsylvania, following a crash over the weekend.

Prosecutors in Bill Cosby's sex assault case in Pennsylvania are fighting efforts by his defence to question 2,000 potential jurors.

A sequestered jury from an outside county will decide the sexual assault case against Bill Cosby, a suburban Philadelphia judge has ruled.

Bill Cosby's lawyers are pushing to have the actor's trial moved from the Philadelphia suburbs because of worldwide media reports that brand him "a serial rapist".

Thinking of the cinema this week. Declan Burke reviews  Fences, Hidden Figures and The Great Wall.

The Irish business mentality needs to change following Brexit or it could stall momentum in the economic recovery, according to American business coach and motivational speaker Keith Ferrazzi.

Shane Lowry will forever remember 2016 as the year he got married and then learned he will become a father five weeks before the 2017 Masters.

Uber is bringing a small number of self-driving cars to its ride-hailing service in San Francisco.

Icelandic airline WOW has announced low-cost fares on its services from Ireland to the United States, via Reykjavik in Iceland.

Furious Donald Trump has accused the FBI of impropriety after the bureau cleared US presidential rival Hillary Clinton of criminal wrongdoing in a new email probe, lifting a cloud hanging over the Democrat as America goes to the polls on Tuesday.