Mutated gene thought to exist in just 4% of people could ‘help tackle obesity’

The team found that it can affect a region of the brain known as the hypothalamus – which controls appetite, food intake, hunger and thirst – by switching on and off the function of other genes there

Scientists have identified a mutated gene helps regulate appetite, weight and insulin (Steve Parsons/PA)

A gene variant that helps regulate body weight could aid in tackling obesity, scientists have said.

The ZFHX3 gene mutation – thought to exist in just 4% of people – has been found to control parts of the brain responsible for appetite.