Lyttle is one of five changes that Ulster have made due to injury and international call-ups. The 19-year-old Academy star, who has scored four tries this season including an opportunist effort against Munster last week when he came on as a replacement, is named on the left wing with Sam Windsor making his debut this season in the midfield alongside Luke Marshall.
Tommy Bowe returns to the right wing with Brett Heron accompanying Ruan Pienaar at half-back. Up front, Pete Browne has got the all-clear from a head knock and packs down for his first run at blindside forward while Sean Reidy, who signed a new three-year deal yesterday, is at openside.
Blonde-haired speedster Lyttle is delighted with his start.”I came down to Ravenhill as a child watching rugby with my parents and all I ever wanted to do was play for Ulster. I can remember coming here with my primary school, Maralin, for a mini rugby tournament and I got my photo taken with Andrew Trimble. I felt this was the greatest thing ever!”
Edinburgh have made five changes in the pack from their starting line-up that lost to Zebre. Frazer McKenzie and James Ritchie start at lock and openside respectively while there is a new front row in Neill Cochrane at hooker and props Jack Cosgrove and Murray McCallum.
B Kinghorn, D Hoyland, C Dean, P Burleigh, T Brown, J Tovey, S Kennedy; J Cosgrove, N Cochrane (capt), M McCallum, F McKenzie, B Toolis, V Mata, J Ritchie, M Bradbury.
S McInally, K Whyte, F Arregui, L Carmichael, C Du Preez, S Hidalgo-Clyne, D Weir, M Allen.
C Piutau; T Bowe, L Marshall, S Windsor, R Lyttle, B Herron, R Pienaar; C Black, R Herring (capt), W Herbst, D Tuohy, F van der Merwe, P Browne, C Ross, S Reidy.
J Andrew, K McCall, A Warwick, R Diack, C Joyce, P Marshall, A Cairns, J Stockdale.