Aidan O’Brien’s former Australian ace suffered a shock loss at the hands of Rewilding in the 10-furlong showpiece 12 months ago and connections will be hoping the six-year-old can put the record straight.
After four reverses in a row, So You Think registered his ninth Group One victory in the Tattersalls Gold Cup with a six-length romp at the Curragh last month.
His stablemate Robin Hood, who was third that day, is likely to be used in the role of pacemaker again.
Carlton House carries the hopes of a notable triumph for The Queen.
Third in the Investec Derby last summer, the Sir Michael Stoute-trained colt made a successful return after a long lay-off in the Brigadier Gerard Stakes at Sandown three weeks ago.
Big Blue Kitten is a fascinating runner from the American stable of Chad Brown while France is represented by Reliable Man, trained by Alain de Royer-Dupre.
Godolphin are double-handed with the unbeaten three-times raced Farhh from Saeed bin Suroor’s yard and Mahmood Al Zarooni’s City Style.
Planteur, Colombian, Sri Putra and Wigmore Hall complete the line-up.
Corine Barande-Barbe has decide not run Cirrus Des Aigles while O’Brien’s other two entries, Excelebration and Windsor Palace, were also absentees.
They are due to take on Frankel in today’s Queen Anne Stakes.
Meanwhile Dunaden and Red Cadeaux could be set to clash again in Saturday’s Hardwicke Stakes.
Mikel Delzangles’ Dunaden beat Ed Dunlop’s Red Cadeaux by a nose in last November’s Melbourne Cup and confirmed superiority in the Hong Kong Vase.
The pair face plenty of competition among 18 entries in the Group Two event as John Gosden has confirmed the fast-improving Aiken, who beat Dunaden in the Grand Prix de Chantilly, and last year’s St Leger winner Masked Marvel.
Last year’s winner Await The Dawn is missing from the Aidan O’Brien squad, while the trainer has included Fame And Glory, presumably if there is a reason he cannot compete in the Gold Cup.
O’Brien can also pick from Memphis Tennessee, Robin Hood, Treasure Beach and Windsor Palace.
Adding strength in depth are Testosterone, a very smart filly in France who has moved to Dunlop and Breeders’ Cup Turf runner-up Sea Moon.
Sir Michael Stoute’s colt just beat another Hardwicke entry, Dandino, on his comeback at Goodwood.
Black Caviar will take on a maximum of 20 rivals in the Diamond Jubilee Stakes, also on Saturday.
The Australian wonder mare has not frightened off all the opposition so far as she seeks to stretch her 100% record to 22 races in the six-furlong Group One.
Peter Moody’s pride and joy could be accompanied by compatriot Ortensia, who is set to run first in the King’s Stand Stakes on Tuesday along with Roger Charlton’s Bated Breath and French raider Wizz Kid.
The James Fanshawe-trained Society Rock will try to repeat his win in this race 12 months ago while Freddie Head’s Moonlight Cloud is another leading fancy.
Among the other overseas possibles are the Bahrain-trained Krypton Factor and Restiadargent from France.
Aidan O’Brien has left in Crusade, Jersey Stakes entry Reply and After.
Other hopefuls include Genki, Hitchens, Pastoral Player, The Cheka and Bogart.
Cape Classic, a leading fancy in the ante-post market, looks unlikely to get a run in Saturday's Wokingham Stakes.
The William Haggas-trained four-year-old needs a host of horses to come out at the final declaration stage for him to make the cut after 85 stood their ground at the confirmation stage and only 28 can go to post.