Robby Ginepri never dropped his serve but still lost out to top seed Andy Roddick 7-6 (9/7) 7-6 (7/2), in an all-American quarter-final at the Regions Morgan Keegan Championships in Memphis.
Ginepri, who blew all four of his break-point chances, slipped to 0-5 lifetime against Roddick, who failed to convert any of his eight break opportunities.
Roddick, who captured the SAP Open title last week in San Jose for his 16th career ATP Tour title and first of the year now meets Denmark’s Kenneth Carlsen in the semi-finals.
Carlsen survived a tough battle before defeating American Jan-Michael Gambill 7-6 (9/7) 7-5.
Eighth seed Max Mirnyi of Belarus also reached the last four with a 7-6 (7/1) 7-6 (7/1) victory over France’s Antony Dupuis.
Mirnyi now faces second seed Tommy Haas of Germany, who improved to 8-2 lifetime against Xavier Malisse of Belgium with a 6-4 6-3 victory over the fifth seed.
In the women’s event, where players are competing for the Cellular South Cup, third seed Meghann Shaughnessy of the United States booked her place in the final with a 7-6 (10/8) 7-6 (8/6) victory over seventh seed Nicole Vaidisova.
The 15-year-old from the Czech Republic saved five match-points in the second set before finally succumbing.
A winner of three WTA Tour titles, Shaughnessy is in her first final since capturing her last title at Canberra in 2003.
The American meets 20-year-old defending champion Vera Zvonareva in the final.
The top seed seed thrashed eighth seed Evgenia Linetskaya 6-4 6-1 in an all-Russian battle.