Tipperary manager John Evans and his Laois counterpart Sean Dempsey have named their sides for Sunday's All-Ireland SFC first round qualifier at Semple Stadium (throw-in 3.30pm).
There are six changes to the Tipp starting line-up from the one which started against Kerry in the Munster SFC quarter-final.
Ciaran McDonald and Chris Aylward are both absent from defence, after going to America for the rest of the summer, along with Alan Moloney.
Attacker Sean Carey has also opted to focus on playing for the Tipperary Under-21 hurlers.
Matthew O'Donnell replaces Paul Fitzgerald between the posts, while Niall Curran and Brian Mulvihill are also absent from the side.
Andrew Morrissey, Brian Jones and Brian Fox come into the Tipperary defence, with Jones and Fox named in the half-back line.
Team captain Robbie Costigan moves from centre-back to full-back.
Stephen Hahessy and Conor Sweeney have been added to the attack, with Hahessy named at right half-forward and Sweeney stationed at left corner forward.
Laois have made four changes to their side that lined out for last Saturday's Leinster SFC quarter-final replay loss to Meath.
Three of the changes are in the half-forward line. Niall Donoher will lead the midlanders' attack, flanked by Billy Sheehan and Padraig Clancy, with Darren Strong and Craig Rogers missing out and John O'Loughlin switching to a defensive role.
O'Loughlin has been positioned at right half-back, with Denis Booth included in the left corner.
Colm Begley has been ruled out through injury, while Cathal Ryan drops to the substitutes bench.
Tipperary and Laois last met in the opening round of NFL Division 2 in February, with the O'Moore men claiming a 1-13 to 1-11 victory.
TIPPERARY (SFC v Laois): M O'Donnell; P Codd, R Costigan, A Morrissey; C McGrath, B Jones, B Fox; G Hannigan, K Mulryan; S Hahessy, H Coghlan, P Acheson; P Austin, B Grogan, C Sweeney.
LAOIS: M Nolan; P O'Leary, M Timmons, D Booth; J O'Loughlin, C Healy, P McMahon; B Quigley, K Meaney; B Sheehan, N Donoher, P Clancy; MJ Tierney, D Kingston, R Munnelly.