Seanie Buckley, Padraig Browne and Michael Crowley will make their first championship starts for Liam Kearns' Limerick in Sunday's Munster SFC semi-final meeting with All-Ireland champions Kerry at the Gaelic Grounds.
The Shannonsiders have failed to beat to Kerry in their last five championship matches, but they did force a replay against Jack O'Connor's side in last year's Munster decider.
Diehard Limerick fans will point to 1922 when the Kingdom were defeated in a walkover win, but truthfully, you have to go back to 1895 to when Limerick got the better of Kerry pitchside in a championship tie.
Kearns will have his aces stacked on Sunday as he attempts to end the county's 110 years of hurt.
Influential midfielder Jason Stokes is back to start his first competitive game in nine months.
Dual players Conor Fitzgerald and Stephen Lucey will also be called upon from the off.
Goalkeeper Seamus O'Donnell also makes his first competitive start since last year's final defeat at the hands of O'Connor's men.
Meanwhile, Waterford boss John Kiely has tinkered with his side ahead of Saturday's opening All-Ireland SFC first round qualifier against Louth in Drogheda.
Kiely, in the aftermath of last month's 2-14 to 2-10 Munster loss at the hands of Clare, claimed he did not care who the Deise men drew in the qualifiers. Louth will provide a stern test for the visitors, however.
Richie Hennessy, Stephen Cunningham, Shane Walsh and Eamon Walsh are Waterford's four new inclusions for the weekend.
LIMERICK (SFC v Kerry): Seamus O'Donnell; Tommy Stack, Johnny McCarthy, Stephen Lavin; Padraig Browne, Stephen Lucey, Conor Mullane; John Quane, Jason Stokes; Michael Crowley, Muiris Gavin, Stephen Kelly; Conor Fitzgerald, John Galvin, Seanie Buckley.
WATERFORD (SFC v Louth): Tom Wall; Paul Ogle, Eamonn Walsh, Richard Hennessy; Andrew Heffernan, Michael Ahern, Trevor Costelloe; Andrew Hubbard, Karl O'Keeffe; Stephen Cunningham, Shane Biggs, Liam Ó Lionain; Niall Curran, Gary Hurney, Shane Walsh.