Joyce rattled the net with a first-half penalty for the 2010 champions as Killererin held a 2-8 to 0-4 lead over Naomh Anna Leitir Mor at half-time.
Goals from Fiachra and Ferdia Breathnach in the opening minutes of the second-half pulled the Gaeltacht men within three, but Joyce sealed the win with two more goals in a 4-15 to 2-12 victory.
Defending champions Corofin left it late to clinch their place in the last-eight and needed two injury-time points from Alan O’Donovan to take a 0-14 to 0-12 win over Cortoon Shamrocks. Corofin trailed by a point at the break, but fought back to 0-12 each after 60 minutes as O’Donovan completed the great escape.
Niall O’Brien’s 1-1 in the first minute proved the difference as An Ceathru Rua got past the challenge of Kilconly.
Just two points separated the sides at the break, but the championship first-timers were unable to take the lead as O’Brien’s quick start proved key.
Last year’s beaten finalists Tuam Stars battled hard before the overcoming a difficult assignment against Mountbellew/Moylough with four unanswered points seeing Tuam to a three-point win.
Four points from Michael Meehan could not save Caltra as St James’ ran out 1-10 to 0-8 on Saturday evening. Paul Conroy and Eoin Concannon inspired the city side to win as a goal from Ronan O’Connell in the second half sealed victory for St James.
The Galway city derby bragging rights belong to Salthill/Knocknacarra after they edged past St Michael’s by the narrowest of margins, 0-13 to 0-12 with Sean Armstrong central to their win.
Elsewhere there were wins for Micheal Breatnachth’s (2-10 to 0-7 over Annaghdown), and for Milltown over Caherlistrane (0-9 to 0-5).