Paddy Nolan comes into the side at full-back in place of Andy Kearns, while James Nolan is named at left corner-forward.
Nolan’s introduction sees a positional reshuffle with Liam Ryan moving to midfield, Martin Walsh switching to left half-back and James Dowling making way.
There are also positional changes in attack with Mark Bergin playing at centre-forward, John Joe Farrell starting at full-forward and senior star Richie Hogan at right-corner-forward.
Opponents Dublin have announced an unchanged side and will field four players who featured in the Leinster SHC final against Kilkenny.
Oisín Gough plays at left corner-back, Simon Lambert is at midfield, David Tracey starts at centre-forward and Liam Rushe is full-forward.
Senior panellists Finn McGarry and Peter Kelly play in goal and at right half-forward respectively. The side also features at centre-back Rory O’Carroll, who dropped himself off the Dublin senior football panel in order to go travelling later in the summer.
DUBLIN U21HC: F McGarry; G Kelly, M Quilty, O Gough; P Schutte, R O’Carroll, R Walsh; S Lambert, C Clinton; P Kelly, D Tracey, P Garbutt; D O’Connor, L Rushe, B O’Rorke.
Subs: K Byrne, J Sheanon, M May, D O’Maoileidigh, D Whelan, A Roche, Darren Kelly, Dean Kelly, K McLoughlin.
KILKENNY U21HC: C McGrath; P Murphy, P Nolan, C Fogarty; L Ryan, D Langton, M Walsh; M Kelly, Liam Ryan; C Fennelly, M Bergin, J Mulhall; R Hogan, JJ Farrell, J Nolan.
Subs: E Murphy, M Walsh, M Phelan, D Lyng, N Cleere, K Hogan, S Maher, P McCarthy, T Breen.