O’Meara missed the concluding stages of the League because of a broken toe, while Curran opted out of the panel early in the season because of college commitments.
Curran has represented Tipp at minor and U21 levels but this will be his senior championship debut.
The inclusion of O’Meara at right half-forward means that John Carroll, who started in that position in the League final which Tipperary lost narrowly to Kilkenny, now moves to full-forward in place of Ger O’Grady.
With Eamon Corcoran ruled out because of a three months ban, Paul Kelly continues at left half-back with Tomas Dunne and Noel Morris renewing their midfield partnership.
Morris has been troubled with a hip injury but received the all-clear to play last night.
Meanwhile, Gary Savage returns to the Down team for Sunday’s Ulster SHC semi-final with Antrim at Casement Park.
Savage missed the one point defeat by Kerry in the last game of the preliminary rounds of the league because of injury but is fully fit again and takes his customary centre half-back slot.
The inclusion of Savage releases his Ballycran team-mate Simon Wilson to resume his centre half-forward duties with Barry Coulter dropping out of the starting equation.
The Down selectors have also made a number of positional changes. Tom Coulter reverts to right corner-back with Gabriel Clarke now at full-back. Gerard Adair, who figured at midfield against Kerry, is now moved to left half-back with Barry Mulligan and Padraigh Monan forming a new midfield partnership.
Although unable to train this week due to a hamstring problem, Gerard McGrattan has been selected in the right corner of attack with Gareth Johnson moving to left corner-forward.
Derry have called up unknown 25-year old Moneymore player Mark O’Neill for their first round Ulster SFC showdown with Allianz National Football League champions Tyrone at Clones on Sunday.
O’Neill has never before represented Derry at inter-county level, be it minor, Under 21 or senior, but is a shock inclusion at left half-forward.
He takes over the position from Johnny McBride, who has been ruled out with a hamstring injury, sustained in training last weekend.
Manager Mickey Moran has also given a first championship start to 22-year-old Ballinderry player Kevin McGuckin. He figured at wing-back during the league but makes his championship debut at left corner-back.
And Moran has also included Anthony Tohill at full-forward.
The brilliant midfielder, who last played in last season’s All-Ireland qualifier when Derry lost to Tyrone, is still battling to overcome the effects of the knee injury which necessitated surgery prior to the start of the league.
TIPPERARY (SH v Clare): B, Cummins; M. Maher, P. Curran, B. Dunne; B. Horgan, D. Kennedy, P. Kelly; T. Dunne, N. Morris; B. O’Meara, C. Gleeson, L. Cahill; E. Kelly, J. Carroll, L. Corbett.
DOWN (SH v Antrim): D. Quinn; T. Coulter, G. Clarke, T. Dorrian; L. Clarke, G. Savage, G. Adair; B. Milligan, P. Monan; M. Coulter, S. Wilson, E. Trainor; G. McGrattan, S. Clarke, G. Johnson.
DERRY (SF V Tyrone): M. Comlan; S. M. Lockhart, N. McCusker, K. McGuckin; P. McFlynn, K. McCloy, K. Doherty; E. Muldoon, F. Doherty; G. Diamond, C. Gilligan, M. O’Neill; P. Bradley, A. Tohill, D. Dougan.