Lab-grown stem cell trial gets green light

Ireland’s first human stem cell trial using lab-grown cells is due to get underway in Galway in the new year following approval from the medicines watchdog.

Lab-grown stem cell trial gets green light

The trial will involve extracting adult mesenchymal stem cells (MSC) from the bone marrow of patients with a condition known as critical limb ischemia (CLI) — a severe blockage of the arteries resulting in marked reduction in blood flow to the extremities.

Reduction in blood flow to the legs puts patients at risk of gangrene, ulceration, and amputation, and the Galway trial will look at the use of MSCs to grow new stems cells which will then be injected back into the patient’s leg with the hope of growing new blood cells and improving circulation.

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