Other hopefuls suggested by members of the public include Northern Ireland First Minister Reverend Ian Paisley, Cardinal Sean Brady, former Taoiseach Dr Garret FitzGerald and Niall Mellon of the Niall Mellon Township Trust.
The Tipperary Peace Convention committee will adjudicate on the nominations and select the winner in early 2008.
Last year Clooney, who has Irish ancestors on his father’s side, spoke in front of the UN Security Council to demand help for the people of Darfur.
The oscar-winning actor has also travelled to Sudan, Chad, Egypt and China as part of his campaigning on the issue.
Last year’s winner of the Tipperary Peace Prize was retired Church of Ireland Archbishop of Armagh Dr Robin Eames and other previous recipients have included Bob Geldof, Mikhail Gorbachev and the late Irish-born Iraqi aid worker Margaret Hassan.
Also nominated this year is Iranian lawyer and former Nobel Prize winner, Shirin Ibadi; Indian spiritual teacher, Sri Sri Ravi Shankar and Suzanne Mubarak — wife of Egyptian president Hosni Mubarak.
Founded in 1984, the Tipperary honour recognises people who promote peace in Ireland and abroad.
The award will be formally presented during the Tipperary International Festival of Peace in Tipperary Town in April.
Other previous winners have included New York Mayor Rudy Giuliani and the New York Fire Department following the 9/11 attacks.