Pathologist: Drugs killed Anna Nicole's son

Anna Nicole Smith’s 20-year-old son died from a lethal combination of methadone and two antidepressant drugs, a US-based pathologist who conducted a private autopsy said yesterday.

Anna Nicole Smith’s 20-year-old son died from a lethal combination of methadone and two antidepressant drugs, a US-based pathologist who conducted a private autopsy said yesterday.

Toxicology tests showed Daniel Smith had methadone, Zoloft and Lexapro in his system when he died on September 10 in a hospital room in the Bahamas where his former Playboy playmate mother was recuperating from giving birth to a daughter, according to Cyril Wecht.

“The fact that we have these drugs and the levels of the drugs overwhelmingly ad most logically point to this being a tragic, accidental, drug-related death,” Wecht said.

Wecht, who performed the autopsy in the Bahamas, said Smith apparently died from a “classical” combination of the drugs which had a lethal “cumulative effect on the central nervous system”.

“Coroners working around the country, we see this in people taking two or three drugs or more,” he said. The low levels of each drug suggest he did not die from an overdose, he added.

Smith had been reported to be suffering from depression in the weeks before he went to the Bahamas to visit his reality TV star mother and his newborn half-sister. Zoloft and Lexapro are antidepressants commonly prescribed for patients with anxiety and panic disorders.

Methadone, a pain-reliever, is also commonly used by people recovering from drug addictions.

“It is used for people who have been on heroin or morphine,” Wecht said. “I have made those inquiries. I can only say to you no one has suggested anything having to do with drug addiction in this boy.”

Lisa Johnson, a pharmacist at Cedars-Sinai Medical Centre in Los Angeles who is not connected with the case, agreed that the combination of the three drugs could be lethal.

“If that’s what he was on, it could very well have caused this,” she said. “The methadone will slow you down, but the other ones make your system speed up, so it’s an odd combination.”

Wecht said he would share his results today with the pathologist who conducted the official autopsy in the Bahamas, but did not know whether they would issue a joint report on the death.

In Nassau, Chief Magistrate Roger Gomez said he has not yet received official toxicology results, which will determine whether or not a jury inquest into the death is necessary.

Smith’s body remained at a Bahamas funeral home hired by the family.

Daniel Smith, who appeared several times on the E! reality series The Anna Nicole Show, was the son of Anna Nicole and Bill Smith, who married in 1985 and divorced two years later.

Anna Nicole married Texas oil tycoon J. Howard Marshall II in 1994, when she was 26 and he was 89. He died the following year and she has since been involved in legal disputes over the estate.

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