Holland play Wales at Cardiff City Stadium on November 13, before taking a trip to Germany for a friendly with the world champions on November 17.
Depay’s exclusion from the 26-man squad could have been accelerated owing to an injury he suffered in a Capital One Cup game last week, although the Manchester United number seven has failed in recent weeks to have the kind of impact many expected since his summer move from PSV Eindhoven.
Blind feels Depay needs to work out his problems quickly to engineer a resurgence for both club and country. He said: “Depay fits qualitatively in the future of Dutch football, but it’s just the way that other issues also play a role. In the world of football you have to be able to function in a team and Depay does not always (do that).”