They will call on third-choice scrum-half Fabien Cibray after Julien Dupuy joined French star Dimitri Yachvili on the sidelines.
Kicking responsibilities for Biarritz look likely to be handed to Damien Traille.
Glasgow go into the game buoyed by last week’s win as well as having secured the signatures of John Barclay and Johnnie Beattie on new contracts.
BIARRITZ: N Brusque; T Ngwenya, P Bidabe, D Traille, B Thiery; J Peyrelongue, F Cibray; E Coetzee, B Noirot, D Avril, J Thion (capt), S Dellape, S Betsen, I Harinordoquy, J Cronje.
Replacements: B August, P Balan, T Hall, S Vahafolau, M Bosch, H Fa’afili, A Willemse.
GLASGOW: B Stortoni; L Fa’atau, A Henderson, D Gibson, H O’Hare; D Parks (capt), S Pinder; J Va’a, F Thomson, M Low, A Newman, D Turner, K Brown, J Barclay, J Beattie.
Replacements: E Milligan, E Kalman, O Palepoi, J Eddie, C O’Young, S Barrow, G Morrison.
Referee: Nigel Owens (Wales)