Having been swept aside by Wales in their 6 Nations opener at the Millennium Stadium last week, it would be difficult to find even a Scot who would back them to beat the world champions at Murrayfield this weekend.
Following the disappointment in Cardiff, Williams has opted to make two changes to his starting 15.
Edinburgh’s Simon Webster will play on the wing and Sale Sharks’ Jason White has been brought into the pack with Allister Hogg and Andrew Henderson both dropping to the bench.
B Hinshelwood (Worcester); S Danielli (Bath), T Philip (Edinburgh), B Laney (Edinburgh), S Webster (Edinburgh); C Paterson (Edinburgh, captain), C Cusiter (The Borders); T Smith (Northampton), G Bulloch (Glasgow, vice captain), B Douglas (The Borders), S Murray (Edinburgh), S Grimes (Newcastle Falcons), J White (Sale Sharks), S Taylor (Edinburgh), C Mather (Glasgow) Substitutes: R Russell (Saracens), G Kerr (Leeds). N Hines (Edinburgh), A Hogg (Edinburgh), M Blair (Edinburgh), D Parks (Glasgow), A Henderson (Glasgow).