All change for Harlequins in their quest to reach quarter-finals

NEC Harlequins make seven changes to the side that started against London Wasps in the Zurich Premiership last Sunday for the Heineken Cup tie against Castres Olympique at Stade Pierre Antoine this afternoon.

Harlequins can’t finish top of Pool Four and need a lot of luck and two bonus-point wins against Castres (second in the pool with 11 points) and Munster (1st, 14) to proceed to the quarter-finals.

The French will fancy their chances of reaching the next round having won their last six home Heineken Cup ties, including decisive victories over Munster and the Ospreys this season.