All change for Harlequins in their quest to reach quarter-finals
Harlequins can’t finish top of Pool Four and need a lot of luck and two bonus-point wins against Castres (second in the pool with 11 points) and Munster (1st, 14) to proceed to the quarter-finals.
The French will fancy their chances of reaching the next round having won their last six home Heineken Cup ties, including decisive victories over Munster and the Ospreys this season.