Roger Federer crashed out at the fourth round of the Sony Ericsson Open in Miami as Tomas Berdych triumphed 6-4 6-7(3/7) 7-6(8/6) in a gruelling battle.
The world number one committed 62 unforced errors and was broken three times as Berdych of the Czech Republic fought through in just under three hours, ending an eight-match losing streak against the Swiss star.
The 16th seed saved eight of 10 break points – with seven of those coming in a tense second set – on his way to the quarter-finals and a clash with Fernando Verdasco.
Rafael Nadal was made to suffer before triumphing 7-6(7/5) 6-4 over compatriot David Ferrer in a gritty affair dominated by unforced errors.
The former World number one edged a tight tie break and raced into a 3-0 lead in the second set but Ferrer rallied, winning the following three games before Nadal broke once again to seal a two-hour victory.
The Spaniard will face eighth seed Jo-Wilfried Tsonga after he dismantled former world number one Juan Carlos Ferrero 6-2 6-2.
Tsonga turned in a fantastic performance as the Frenchman dropped just four points on his first serve.
Andy Roddick recovered from an awful start to eventually book his place in the final eight.
The American, seeded sixth, trailed 1-4 and 0-40 to Germany’s Benjamin Becker in the first set as he struggled with his accuracy early on.
But the three-time Wimbledon finalist showed his tenacity to respond superbly and take the set to a tie-break, which he won 7-4.
Roddick, who won this tournament in 2004, then broke for a 4-2 lead in the second set on his way to prevailing 6-3.
Roddick will now face Spain’s Nicolas Almagro in the last eight after he defeated Brazil’s Thomaz Bellucci 6-4 3-6 7-6 (7-3).
Number five seed Robin Soderling is also through following a 6-0 6-7(3/7) 6-2 victory over Fernando Gonzalez.
However, in-form Croat Marin Cilic is out after Verdasco swept the seventh seed aside 6-4 7-6(7/3).
Andy Murray’s conqueror, Mardy Fish, is also out after the American was forced to retire while trailing 6-1 1-0 against 13th seed Mikhail Youzhny.