The Waterford hurlers will be without the services of Maurice Shanahan for the next "four to six weeks".
Shanahan suffered ankle ligament damage during Waterford's defeat to Tipperary in last Saturday's Allianz Hurling League opener in Thurles.
The Waterford management have confirmed that the influential forward, who turned 24 earlier this month, is unlikely to play any further part in the Déise's league campaign.
Shanahan is a younger brother of former Hurler of the Year and current Waterford selector Dan Shanahan. He was the sixth top scorer in the 2013 Hurling Championship with 1-29.
He had been included in an unchanged Waterford team for next Sunday's Division 1A match at home to Galway, but manager Derek McGrath will have to draft in a replacement.
Another of Waterford's forward contingent, the veteran Seamus Prendergast, could be about to join Shanahan on the sidelines.
He sustained a suspected fracture in his hand after coming on as a substitute on the hour mark against Tipp, and is awaiting the results of a scan.
WATERFORD (NHL v Galway): Stephen O'Keeffe; Barry Coughlan, Shane Fives, Noel Connors; Jamie Nagle, Michael Walsh (capt), Philip Mahony, Kevin Moran, Shane O'Sullivan; Jamie Barron, Pauric Mahony, Jake Dillon; AN Other, Shane Walsh, Brian O'Sullivan.