PJ Banville will make his first start of the 2011 Championship when Wexford meet Limerick in Portlaoise on Saturday night (throw-in 7pm).
Banville will have a wing forward role against the Shannonsiders, after featuring off the bench in Wexford's recent runouts against Carlow and Dublin.
The Horeswood clubman comes in for Shane Roche in a rejigged attack. The free-scoring Ciarán Lyng and Ben Brosnan complete the half-forward line, with Adamstown's Eric Bradley moved in to the edge of the square.
Captain David Murphy was a doubtful starter earlier in the week due to a back injury, but the centre-back is winning his race to be fit for Wexford's fifth match of the summer.
Their qualifier opponents this weekend, Limerick, have beaten Offaly and Waterford over successive weekends while Wexford have only played once in the past three weeks.
The Model men's preparations have also been limited by club Championship matches last weekend and to avoid any late injuries, the panel only trained together last Sunday morning and on Tuesday evening.
Ryan told the Wexford Echo: "Limerick have won two games in-a-row, so it gives them a huge boost. They had an emphatic win over Offaly, while they maybe gave a more battling performance against Waterford last Saturday.
"But a win is a win, and the fact Limerick have been together both last week and this week is a major boost to their preparations, whereas our squad had to break up."
WEXFORD (SFC v Limerick): Anthony Masterson; Joey Wadding, Graeme Molloy, Brian Malone; Adrian Flynn, David Murphy (capt), Aindreas Doyle; Daithí Waters, Rory Quinlivan; PJ Banville, Ciarán Lyng, Ben Brosnan; Colm Morris, Eric Bradley, Redmond Barry