The vastly-experienced Brian Dooher will start for Tyrone against Monaghan in Sunday's Ulster SFC quarter-final at Healy Park (throw-in 3.30pm).
In his seventh season as captain of the Red Hands, Dooher is expected to last the pace after featuring as a substitute in the closing rounds of the Allianz Football League against Kildare and Meath.
An extended winter break and a four-week suspension, picked up whilst playing for Clan na nGael against Loughmacrory, has meant the 35-year-old has played little competitive football in recent months.
But Tyrone manager Mickey Harte is backing Dooher to lead the team to victory in the first game of their Ulster title defence.
The selected side also includes Championship debutant Mark Donnelly and Dooher's club-mate Stephen O'Neill, who join Martin Penrose in the full-forward.
Another former All-Ireland winner, Philip Jordan, has been selected at wing back despite his lack of game-time so far this year. There were rumours that Jordan was considering his inter-county future, but he is committed to another campaign.
Former Footballer of the Year Sean Cavanagh has recovered from an elbow injury to take his place in midfield alongside Aidan Cassidy.
Martin Swift replaces the injured Justin McMahon in the full-back line, with McMahon's brother Joe, Enda McGinley, goalkeeper Jonny Curran and Ronan McNabb all nursing knocks.
In all, there are ten survivors from the Tyrone team that lost to Dublin in last year's All-Ireland quarter-final. The McMahons, Kevin Hughes, Colm Cavanagh and Owen Mulligan are the five players not included this time.
TYRONE (SFC v Monaghan): Pascal McConnell; Martin Swift, Cathal McCarron, Ryan McMenamin; Davy Harte, Conor Gormley, Philip Jordan; Aidan Cassidy, Sean Cavanagh; Brian Dooher (capt), Brian McGuigan, Peter Harte; Martin Penrose, Mark Donnelly, Stephen O'Neill.