If a motion of no confidence in the Taoiseach or the Government is passed, or a motion of confidence is defeated, the Constitution dictates that both the Taoiseach and the Government must then resign. Theoretically the Government could stay in place if it loses a vote relating to a Minister, but in practice this would be almost impossible.
Sinn Féin has chosen to use its speaking slot on Wednesday to put down a no-confidence motion in Simon Coveney at around 6pm.
But the Government are likely to change the Dáil schedule and will put forward a countermotion of confidence in Mr Coveney ahead of this, likely to be around 3pm which will involve a number of speeches defending the Foreign Affairs Minister, before a vote is taken.
A motion of confidence or no-confidence requires a full vote. Current Covid restrictions mean the Dáil chamber is limited to 50% capacity so not all TDs will be allowed sit in their allocated seats.
Instead some politicians will stand in the voting lobby area around the chamber and others members will be asked to sit in the public gallery to allow for a roll-call ballot.
The Taoiseach has already indicated that all Fianna Fáil members will be expected to back Mr Coveney in any vote. Sinn Féin, having tabled the motion, will vote against any countermotion put down by the Government.
The Labour party and the Social Democrats are excepted to do the same, along with a handful of Independents. But overall, Mr Coveney will have the numbers in Government and his position will remain secure.