Irish researchers make breakthrough in battle against incurable childhood cancer 

Geneticists from Trinity College Dublin discovered that the mutation – H3K27M – causes diffuse midline glioma (DMG), and – in lab studies working with model cell types – successfully reversed its effects to slow cancer cell growth with a drug. Picture: Pexels

Geneticists from Trinity College Dublin have pinpointed how a gene mutation causes an incurable childhood cancer and have successfully targeted tumour cells with a tailored drug.

The researchers discovered that the mutation – H3K27M – causes diffuse midline glioma (DMG), and – in lab studies working with model cell types – successfully reversed its effects to slow cancer cell growth with a drug.