The Irish Medicines Board says it has received 64 reports of adverse affects associated with the use of Gardasil.
The vaccine is being administered to secondary school students to protect against cervical cancer.
The HPV Schools Immunisation Programme started in May this year and an estimated 45,000 doses have been administered.
The IMB says it has received 64 reports of adverse events associated with use of Gardasil, 55 of which were received since the beginning of the Schools Immunisation Programme, with nine prior to this.
The Medicines Board says the majority of reports have been consistent with the expected pattern of adverse effects for the vaccine, as outlined in the product information.