Families in ADHD genetic link study
The Pan European and Pan American Image Study, involves taking four blood samples from 1,400 families where a child has attention deficit hyperactivity disorder (ADHD).
Trinity College-based Dr Aisling Mulligan, who is involved in the Irish research, said while previous minor studies had indicated a link between certain genes and ADHD, this was the first major research project to examine the relationship.
“It will involve taking blood samples from families across Europe and America, including a blood sample from the child with ADHD, a blood sample from a brother or sister and a blood sample from one or both parents,” said Dr Mulligan.
So far, the research in Ireland has involved clinical work - meeting with the families, discussing the symptoms the child displays and taking the blood samples.
However, Dr Mulligan said they will shortly embark on “genotyping” - a technique to identify mapping of genes - through an analysis of the blood samples.
“It is a five-year plan and we are one-and-a-half years down the line in Ireland. It is too early to say if our research will show a genetic link with ADHD, but previous studies point towards genetics being an important factor,” said Dr Mulligan.
ADHD can be defined as a persistent pattern of inattention and/or hyperactivity-impulsivity that is more frequent and severe than is typical for others at a similar level of development.
It is a neurobiological disorder that affects 3%-5% of school-age children, which in Ireland is up to 80,000 children. Until recent years, it was believed children outgrew ADHD in adolescence. However, it is now known that many symptoms continue into adulthood.
Last year, a study found young people with ADHD are more likely to drink alcohol, smoke and use illegal drugs.
Dr Mulligan said more families are being sought to participate in the Irish aspect of the Image Study.
Anyone interested in taking part can contact Dr Mulligan on 01-6082464.
