Apple is once again Ireland's largest company with sales of almost €120bn.

Firms in Cork have been encouraged to practice so-called ‘social innovation’ by engaging in community projects and not only raising funds for good causes.

These are good days for Ireland’s manufacturers as a resurgent economy driven by home-grown and foreign investment provide the biggest turnaround since the financial collapse 10 years ago, writes John Whelan 

Since the opening of Digital Equipment Corporation in Galway in 1971 its legacy — now in the guise of Hewlett Packard Enterprise — is still as strong as ever, writes Dr Chris Coughlan.

More than 260 jobs have been announced in Athlone and Galway — with 70 to be filled by Christmas.

US Democratic presidential candidate Hillary Clinton will unveil proposals to deter US companies from shifting profits overseas, including an “exit tax” to penalise firms that perform so-called tax inversions, a campaign official said.

Good morning. Here’s everything you need to know before you start your day.

The Irish arm of social media giant Twitter last year returned to profit, new documents show.

The huge strengths of Ireland’s exporting base — which helped the country get through its worst ever economic crisis — were highlighted yesterday in the annual publication of the list of the top exporters on the island.

Taoiseach Enda Kenny and the sons of the late actor and comedian Dermot Morgan are backing a new campaign to encourage greater awareness of the risks of high blood pressure.

Damien Hayes, in reflecting on Portumna’s journey to the 2014 All-Ireland club hurling decider, cited their county quarter-final fixture against Ardrahan as the most troublesome hurdle.

It looks like an MP3 player but this small device is aimed at helping diabetics avoid hypoglycemic attacks, also known as “hypos”, by copying the body’s own control system.

AIB All-Ireland Club SHC semi-final: Gort v Ballyhale: Gort hurling captain Greg Lally is the team’s indisputable leader since the emigration of former captain Andy Coen to Canada last year and he will be expected to lead the side from centre-back in tomorrow’s All-Ireland Club SHC semi-final against Ballyhale Shamrocks.

Doctors for a man, suing the makers of an allegedly faulty heart defibrillator, believe that removing the device now would pose a greater risk than leaving it in place.

US investors remained in a record-setting mood, edging the Dow Jones industrial average and Standard & Poor’s 500 index to their latest all-time highs.

Twitter’s Irish-based operation recorded a loss last year, as its cost base increased sharply following moves to double its workforce in Dublin.

Medtronic, the Minnesota- based medical device maker that’s planning to take an Irish tax address, may become one of the biggest losers under rules announced today by the Obama administration.

US treasury secretary Jacob Lew said the department is finishing work to limit the benefits companies gain from moving their addresses overseas even if his action won’t be enough to stop the practice known as inversion.

A record €39.3bn worth of mergers and acquisitions were recorded in Ireland in the opening half of 2014, representing a dramatic increase on the same period a year previously.

Medtronic plans to pick up a $25m tax bill for chief executive Omar Ishrak, the cost of a special penalty imposed by Congress on executives who shift their company’s tax domiciles out of the US.

Covidien plc, the Irish maker of surgical accessories and operating-room products, was sued by a shareholder over claims the company’s planned sale to US competitor Medtronic will enrich directors and managers by almost $96 million (€72.7m) in cash at the expense of investors.

Nearly 18,500 mergers and acquisitions (M&A) worth $1.7trn (€1.28trn) have been completed this year.

Medtronic, the medical technology company poised to buy the Dublin-based Covidien plc and move here for tax purposes, said its quarterly sales grew 5% as demand rose for its pacemakers and aortic valves. 

President Barack Obama plans to go on the offensive against companies that use cross-borders mergers to escape US taxes, accusing them of essentially renouncing their citizenship to shield profits.

Salix Pharmaceuticals has agreed to buy the patents to some drugs for gastrointestinal diseases from Cosmo Pharmaceuticals for about $2.7bn (€1.98bn) in stock in a deal that will allow the US company to move to Ireland and lower its tax bill.

A spate of takeover activity in the pharmaceutical sector pushed Irish-related acquisition values to a 20-year high in the first half of 2014 and saw the country account for nearly 18% of European merger activity, in value terms.

For decades, medical technology firms have searched for ways to let diabetics check blood sugar easily, with scant success.

Shares in Shire hit a record high yesterday on expectations of a takeover as dealmaking sweeps the drugs sector, after Reuters reported the group had hired investment bank Citi as a defence adviser.

US medical device maker Medtronic Inc has said it agreed to buy Dublin-based Covidien Plc for $42.9bn (€31.6bn) and shift its executive headquarters to Ireland in the latest move by US firms to harvest lower corporate tax rates abroad.

SIPTU has requested an immediate meeting with the management of Covidien following today's announcement that the medical device manufacturer has agreed to be acquired by Medtronic.

Medtronic, the world’s biggest maker of heart-rhythm devices, said fiscal first-quarter sales missed analysts’ estimates on weaker-than-expected demand for defibrillators and the InFuse bone-growth product.

The world’s biggest maker of heart-rhythm devices, said fourth-quarter sales of pacemakers and defibrillators rose, surprising analysts.

The iPad 2 can be bad for your heart — with a study showing is some cases the tablets interfere with lifesaving heart devices because of the magnets inside.

The €300m funding for seven research centres by Government and 150 industry partners is a major step on our road to recovery, writes Seán Sherlock

Medtronic reported higher quarterly earnings yesterday but sales of key heart and spine devices fell and overall European sales weakened in January, sending the company’s shares down nearly 3%.

Medtronic, the world’s biggest maker of heart-rhythm devices, said first-quarter profit climbed 5.2% as doctors embraced the company’s newest drug-coated stent to prop open clogged arteries.

European Commissioner for Research, Innovation and Science Máire Geoghegan-Quinn has called for a 'yes' vote in the upcoming referendum on the EU Fiscal Compact.

Medtronic Inc, the world’s biggest maker of heart-rhythm devices, said fiscal third-quarter profit increased 1.2% as rising global demand for pacemakers eased a slump in sales of defibrillators and spinal products.

Pre-tax profits at the main Irish subsidiary of one of the biggest employers in the State, US medical device manufacturer, Medtronic last year decreased by 21% to €149.8 million.

FOUR weeks ago in the Galway county football final, Alan O’Donovan, Corofin’s corner-forward, shot ten points against Tuam Stars.

ANDY COEN was just two the last time Gort won the Galway senior hurling title, in 1983.

MEDTRONIC Inc (MDT), the world’s biggest maker of heart-rhythm devices, said first-quarter profit fell 1.1% as demand for its defibrillators and spinal products declined and costs to produce them rose.