Biogen sets out plan for development of Alzheimer's drug

Since the approval of Aduhelm in June last year, the value of Biogen shares have nearly halved.

The new drug, Lecanemab, is crucial for the growth of the drugmaker as it faces competition for several of its blockbuster drugs, including multiple sclerosis treatment Tecfidera.

Drugs giant Biogen tried to assuage investor worries by laying out a plan for its Alzheimer's disease drug being developed with Eisai and promising to draw lessons from the setbacks to its treatment Aduhelm.

The new drug, Lecanemab, is crucial for the growth of the drugmaker as it faces competition for several of its blockbuster drugs, including multiple sclerosis treatment Tecfidera.

Company executives said data from a trial of Lecanemab is expected in the autumn. Biogen and Eisai have filed for an accelerated approval and the US regulator has set a January deadline.

"We'll take learnings from Aduhelm as necessary and where we can and we'll resource (the launch) at each phase of its commercialization very gradually," chief financial officer Michael McDonnell said.

Last year, Aduhelm became the first treatment for Alzheimer's disease to be approved in the United States in decades, but Medicare, the US government's health plan for people over age 65, sharply curtailed its use on efficacy concerns.

Biogen in May had to significantly pull back the sale of Aduhelm. Since the approval of the drug in June last year, the value of Biogen shares have nearly halved.

The shares were trading 2% lower even as the drugmaker raised its full-year profit forecast by relying on the sales of Tecfidera. Its sales fell 18% to $397.9m (€390m), but was above expectations of $367.7m. 

"We suspect investors are not likely to be satisfied by upside from such legacy products," Piper Sandler analyst Christopher Raymond said.

Biogen now expects annual profit to be in the range of $15.25 to $16.75 per share compared to prior forecast of $14.25 to $16. 

Reuters