A further four Covid-19 clusters have been confirmed in meat processing plants in the past seven days, bringing the total to 16.
They account for 828 cases, an increase of 328 over the week.
Meat Industry Ireland said it is disappointed by the rise and is taking guidance from the HSE to prevent further outbreaks.
Deputy chief medical officer Ronan Glynn said the trend is "worrying".
"There is a national outbreak control team in place," he said.
"It is concerning and certain it will be one of the topics for our NPHET discussion this Friday."
He added: "Just to say as well those part of the work that the outbreak team is doing, I know guidance is issued to all of the facilities and employers, setting out the kids of steps that should be taken to mitigate the worst effects in those settings."
- The HSE have developed an information pack on how to protect yourself and others from coronavirus. Read it here
- Anyone with symptoms of coronavirus who has been in close contact with a confirmed case in the last 14 days should isolate themselves from other people - this means going into a different, well-ventilated room alone, with a phone; phone their GP, or emergency department;
- GPs Out of Hours services are not in a position to order testing for patients with normal cold and flu-like symptoms. HSELive is an information line and similarly not in a position to order testing for members of the public. The public is asked to reserve 112/999 for medical emergencies at all times.
- ALONE has launched a national support line and additional supports for older people who have concerns or are facing difficulties relating to the outbreak of COVID-19 (Coronavirus) in Ireland. The support line will be open seven days a week, 8am-8pm, by calling 0818 222 024