The Palestinian president hit out at US president Donald Trump in a fiery, two-hour-long speech on Sunday, saying "shame on you" for his treatment of the Palestinians.
He also warned he would have no problem rejecting what he suggested would be an unacceptable peace plan.
The speech by Mahmoud Abbas ratcheted up what has been more than a month of harsh rhetoric toward Mr Trump since the president’s recognition of Jerusalem as Israel’s capital.
Relations between Washington and the Palestinians have sunk to a new low, boding poorly for a peace plan the White House has promised to present.
Speaking to the Palestinian Central Council, a decision-making body, Mr Abbas repeated the Palestinians’ opposition to Mr Trump’s Jerusalem recognition and censured Mr Trump for accusing the Palestinians of refusing to negotiate.
"He (Trump) said in a tweet: ’We won’t give money to the Palestinians because they rejected the negotiations’," Mr Abbas said.
"Shame on you. When did we reject the talks? Where is the negotiation that we rejected?"
Mr Trump infuriated Palestinians and Muslims around the world when he announced late last year that the US would recognise Jerusalem as the capital of Israel and move its embassy there, upending decades of US policy and countering an international consensus that the fate of Jerusalem should be decided in negotiations between the sides.
Mr Abbas has said that by siding with the Israelis on a sensitive issue, the announcement had destroyed Mr Trump’s credibility as a Mideast peace broker.
"We can say no to anyone if things are related to our fate and our people, and now we have said no to Mr Trump," he said.
"We told him the deal of the century was the slap of the century. But we will slap back."
Mr Abbas also said that the Palestinians have rejected a US request to halt payments to roughly 35,000 families of Palestinians killed and wounded in the conflict with Israel, including suicide bombers and other militants.
Israel argues that the practice encourages violence.
Hoping to secure what he has called the "ultimate" deal, Mr Trump has for nearly a year dispatched his Mideast team, led by his adviser and son-in-law Jared Kushner, to the region to try to breathe life into moribund peace talks, which collapsed in 2014.
But the Jerusalem pivot threw a wrench into Mr Trump’s peacemaking attempts.
Since then, the Palestinians have butted heads with the US at the United Nations, winning a global rebuke against Mr Trump’s move.
Mr Trump has responded by threatening to cut aid and to reduce US payments to the UN’s Palestinian refugee agency.
The US is the largest donor to the agency.
Israeli prime minister Benjamin Netanyahu has welcomed Mr Trump’s tough line toward the Palestinians, while also pushing forward with more settlement construction on lands sought by the Palestinians.
Palestinian officials say that while they have not received a formal proposal from the US, they have heard from Saudi interlocutors that the US is exploring the possibility of offering the Palestinians a statelet in the parts of the West Bank they already control, with Israel controlling the borders, and the Gaza Strip.
US officials have not confirmed the claims.
But if true, the proposal would fall far short of Palestinian claims to the West Bank, east Jerusalem and Gaza for an independent state.
Mr Abbas said the Palestinians will not accept the US as a sole broker, and believe a deal can only be reached if there are multiple parties, such as with the international nuclear deal between six global powers and Iran.