US President George W Bush is due to arrive in China on his first trip outside the United States since the September 11 terror attacks.
Mr Bush will join 21 Pacific Rim leaders at the Asia-Pacific Economic Co-operation forum in Shanghai, but will also use the trip to push for support for his war on terrorism.
He will meet Russian premier Vladimir Putin for the first time since the atrocities, and also have talks with Chinese president Jiang Zemin.
And he will also meet Indonesian leaders for the first time since Americans were warned to leave the world's most populous Muslim country as demonstrations by supporters of Osama bin Laden sparked riots in several cities.
Speaking before he boarded Air Force One to go to China, Mr Bush said: "Of course, we'll talk about economics and trade.
"But the main thing that will be on my mind is to continue to rally the world against terrorists."
Mr Bush said he would remind other leaders at the forum that "evil knows no borders, no boundaries".
"And remind them that we must take a stand," he added.
Some of the countries at the conference are dealing with radical Islamic groups linked to bin Laden, including the Philippines, where the breakaway Abu Sayyaf rebel group has kidnapped a series of Americans and is conducting a guerilla war.
Others, such as China and Russia, not only have al Qaida operatives in their territory but could provide the United States with critical intelligence information.