Jennifer Aniston and Justin Theroux's big day in Bel Air

US actress Jennifer Aniston and actor-director Justin Theroux tied the knot on Wednesday in a ceremony at their Bel Air home in front of more than 70 friends and family members, according to People magazine.

Guests included celebrities Lisa Kudrow, Chelsea Handler and Howard Stern.

Aniston, 46, and Theroux, who turns 44 next Monday, met while Aniston was on vacation in Hawaii with her friend and former Friends co-star Courteney Cox.