Viagra helps to relax the heart, study reveals
The impotency drug causes overly rigid heart chamber walls to become more elastic and might benefit patients with diastolic heart failure.
People with the condition have abnormally inflexible ventricles, the heart’s major pumping chambers, that do not fill sufficiently with blood.
This leads to blood “backing up” in the lungs and breathing difficulties.
Scientists found that Viagra activates an enzyme that causes a protein in heart muscle cells to relax.
The effect was seen in dogs with diastolic heart failure within minutes of the drug being administered.
Professor Wolfgang Linke, from Ruhr Universitat Bochum in Germany, said: “We have developed a therapy in an animal model that, for the first time, also raises hopes for the successful treatment of patients.”
Viagra has a similar effect on blood vessels, which is why it was originally developed as a treatment for high blood pressure and heart disease.
The drug’s active ingredient, sildenafil, inhibits an enzyme involved in the mechanism that regulates blood flow.
However, the enzyme is slightly different in different parts of the body.
The scientists behind Viagra found to their initial disappointment that it was not a great help to patients with high blood pressure. But it had a miraculous effect on men with erectile dysfunction.




