Stress hormone linked to depression

A HORMONE released during period of long-term stress has been directly linked to depression for the first time.

Scientists already knew that many people with depression have high levels of the stress hormone cortisol. But it was not clear whether cortisol caused the condition or was a consequence of it. The new study in mice provides strong evidence that long-term exposure to cortisol contributes to the symptoms of depression.

In humans, ongoing chronic stress, such as caring for a spouse with dementia, has been associated with depression.