Manchester United suffered a double blow with Wayne Rooney and Nemanja Vidic ruled out of this Champions League semi-final second leg match.
Rooney took a knock to the hip in the defeat by Chelsea at the weekend while Vidic suffered a facial injury.
Manager Alex Ferguson made six changes to his side as they looked to book a place in the final in Moscow with the scores locked at 0-0.
Top scorer Cristiano Ronaldo returned to the starting line-up along with Carlos Tevez, Owen Hargreaves, Patrice Evra, Paul Scholes and Park Ji-Sung.
Former Arsenal star Thierry Henry had to settle for a place on the Barcelona bench.
Man Utd: Van der Sar, Hargreaves, Ferdinand, Brown, Evra, Park, Scholes, Carrick, Nani, Ronaldo, Tevez.
Subs: Kuszczak, Anderson, Giggs, O’Shea, Fletcher, Silvestre, Welbeck.
Barcelona: Valdes, Zambrotta, Puyol, Milito, Abidal, Toure Yaya, Messi, Xavi, Deco, Iniesta, Eto’o.
Subs: Pinto, Gudjohnsen, Henry, Edmilson, Sylvinho, Thuram, Bojan.
Referee: Herbert Fandel (Germany)