Llorente strikes to seal passage for Villareal
Llorente replaced the ineffective Nihat at half-time, but it was Ariel Ibagaza who stunned the OACA Spiros Louis stadium crowd with a sumptuous strike to open the scoring just four minutes in.
Pana fought back, winning a series of corners and they were rewarded for their pressure six minutes later when Mantzios powered a header past Lopez. Villarreal took the lead for the second time in the match with 20 minutes remaining when substitute Llorente drilled home.