Eric Elwood has named a side which shows only one change to the starting XV following last Friday's 22-14 win over Biarritz for the return Heineken Cup Pool 3 fixture at the Parc des Sports Aguilera on Friday (8pm).
Johnny O'Connor replaces Willie Faloon in the back row where he is joined by Andrew Browne and Eoin McKeon.
Faloon was ruled out of selection earlier this week due to a fractured eye socket he incurred at the Sportsground on Friday night.
Dan Parks will lead his side out tomorrow night as Connacht look for a historic French double. Parks is this season's leading points scorer on 48 points, bringing his all-time total to 403 points.
The out-half is two points short of reaching the half-century mark in the Heineken Cup for the fifth time in eight seasons.
19-year-old Robbie Henshaw, who this week signed a full contract with Connacht Rugby, will line out at full-back.
On the bench, forwards Nathan White and George Naoupu make a welcome return to the squad having both missed out on last week's round three clash.
Gavin Duffy, Mata Fifita, Eoin Griffin, Shane Layden, Darragh Leader, John Muldoon, Frank Murphy, Dave Nolan remain unavailable for selection due to injury.
Centre Kyle Tonetti has been in Germany this week undergoing intensive treatment on his recurring hamstring problem and is return to Connacht early next week and hopes to be back training in the next two weeks.
Connacht (v. Biarritz): R Henshaw; T O’Halloran, D Poolman, D McSharry, F Vainikolo; D Parks (capt), K Marmion; B Wilkinson, J Harris-Wright, R Loughney, M Kearney, M McCarthy; A Browne, J O’Connor, E McKeon.
Replacements: E Reynecke, D Buckley, N White, D Qualter, G Naoupu, P O’Donohoe, M Nikora, M Jarvis.