Kieron Dawson and Chris Sheasby return to the Exiles back row for Friday's Zurich Premiership showdown with Leeds Tykes at Headingley Stadium.
Barry Everitt is in the squad for the first time in seven weeks having recovered from a hamstring injury.
Unavailable for selection due to injury are: Kevin Burke (shoulder), Pierre Durant (neck), Rob Hardwick (knee), Nick Kennedy (knee) and Phil Murphy (hamstring).
Commenting on the match, Head Coach, Gary Gold said: “While we were disappointed to be knocked out of Europe, we have benefited from the fortnight’s break from competition by training and working hard on our game for the rest of the season.
"Our return to Zurich Premiership action could not be more demanding than an away visit to Leeds Tykes. Securing points at Headingly has proved difficult for us over the past two seasons and I have no doubt that Phil Davies and his team will be determined that this will not change on Friday night.”
LONDON IRISH: 15. Michael Horak*; 14. Paul Sackey; 13. Geoff Appleford*; 12. Rob Hoadley; 11. Justin Bishop*; 10. Mark Mapletoft*; 9. Darren Edwards; 1. Neal Hatley; 2. Naka Drotske*; 3. Doug Wheatley; 4. Ryan Strudwick (captain); 5. Bob Casey*; 6. Declan Danaher; 7. Kieron Dawson*; 8. Chris Sheasby*.
Substitutes: 16. Adam Halsey; 17. Adrian Flavin; 18. Kieran Roche; 19. Paul Gustard; 20. Delon Armitage; 21. Kevin Barrett; 22. Barry Everitt.
* denotes international.