Former Scotland skipper Budge Pountney, ex-Wales captain Scott Quinnell and South Africans Andre Vos and Josh Kronfeld have been ruled out of the Barbarians side to face England at Twickenham on Sunday through injury.
Flankers Vos and Kronfeld were injured playing against each other for Harlequins and Leicester respectively in last week’s Zurich Premiership wild card play-offs.
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