Henry Cecil’s brilliant colt has overcome a slight leg injury a few weeks ago to take his place in the Group One over the straight mile.
Frankel, owned by Khalid Abdullah, has shown his well-being recently and delighted connections in workouts at Newmarket.
The four-year-old has already won five races at the highest level, and a total of nine in all.
He will be joined to post by his close relative and regular work companion Bullet Train.
Richard Hannon, who has won the last two running of this race with Paco Boy and Canford Cliffs, has declared Strong Suit and Dubawi Gold.
However, the Marlborough trainer warned Strong Suit will not run unless the ground is suitable.
“If there’s any soft in the ground he probably may not run,” said Hannon.
“Dubawi Gold definitely runs.”
Excelebration was put in his place by Frankel three times last season, when trained by Marco Botti.
Now with Aidan O’Brien, the Prix du Moulin winner tries again on the back of a pleasing victory on his first run for the Irish trainer in the Gladness Stakes at the Curragh last month.
O’Brien also has a second string to his bow in Windsor Palace, who floored stablemate St Nicholas Abbey in the Mooresbridge Stakes at the Curragh earlier this month.
Ransom Note, trained by Charlie Hills, completes the seven-strong line-up.
So You Think and Red Jazz were the only withdrawals at the 48-hour final declaration stage.
Meanwhile, Red Cadeaux continues the first part of a varied programme for 2012 when he lines up for the Sportingbet Yorkshire Cup today.
Ed Dunlop’s globetrotting six-year-old ran tremendous races towards the end of last term in the Irish St Leger, Melbourne Cup and Hong Kong Vase.
Another ambitious campaign is being mapped out for Red Cadeaux, who made an encouraging return to action when runner-up to Colour Vision in the Sagaro Stakes at Kempton two weeks ago.
“Everything’s gone well since the Sagaro and he seems in good form,” said Dunlop.
“As expected, it’s a competitive race and we hope for the best.
“This race fits in well with his programme.
“The ground might dry out a bit but it will still be decent good ground so we won’t worry about that unless the jockeys say anything differently.
“We wanted to have a fairly early campaign – he might or might not go to Royal Ascot after this – then have a break and come back for an autumn campaign which will include going back to Australia for the Melbourne Cup.”