The David Johnson-owned grey landed the Paddy Power Gold Cup last month and also ran a screamer when fourth in the Hennessy at Newbury as his stamina just ran out close home.
He is due to return to two miles and five furlongs for this weekend’s Prestbury Park feature, in which he finished second to Poquelin 12 months ago.
Pipe has also left in last Saturday’s Tingle Creek fourth I’msingingtheblues, Matuhi, who was brought down in the Galway Plate when last seen, and Salut Flo, off the track since just failing to bring up the hat-trick over 600 days ago.
“I left four in the Spinal Research The Atlantic 4 Gold Cup and the intention is to run them all if possible,” said Pipe.
“Great Endeavour seems well at home and it looks likely he will take his chance. I’msingingtheblues ran a cracking race in the Tingle Creek. Both Great Endeavour and I’msingingtheblues will like the better ground at Cheltenham and so will Matuhi.
“Salut Flo has been off a long time and he is the one who would appreciate some rain before the weekend.”
With Great Endeavour being given the green light, it means the first three from the Paddy Power will all meet again as Ferdy Murphy’s Divers (third) is on target along with runner-up Quantitativeeasing.
The latter is more likely to represent Henderson than stablemate Nadiya De La Vega.
“Both of mine are JP’s (owner JP McManus) and I would have thought only one of them will run and that is most likely to be Quantitativeeasing,” said Henderson.
“He ran a great race in the Paddy Power and has been very well since. I could have done without him going up in the ratings but otherwise I am happy with the horse.”
Poquelin would have been going for a third successive win in the race but owner Andy Stewart, who sponsors the race, revealed on Sunday that he had met with a small setback and would not be running.
Stewart could still have a few strings to his bow, however, as he owns Ghizao in partnership with Johnson and has Tatenen and Nomecheki still engaged.
The weights are due to go up 4lb in Poquelin’s absence with stablemate Woolcombe Folly at the head of affairs.
Willie Mullins’ recent Naas winner Quel Esprit leads the Irish challenge and if his jumping stands up to scrutiny he will be a danger to all.
Roberto Goldback and Finger Onthe Pulse, who landed the 2010 Galway Plate, complete the Irish entry.
Stan James bet: 11-2 Quantitativeeasing, 8-1 Great Endeavour, Ghizao, 9-1 Divers, 10-1 Quel Esprit, 12-1 bar.
OSCAR WHISKY is the star among 10 entries for the Unicoin Homes Relkeel Hurdle at Cheltenham on Saturday.
Nicky Henderson’s six-year-old finished third in the Champion Hurdle last March and looked set to give subsequent Fighting Fifth winner Overturn a run for his money on his return at Ascot before falling at the last.
Henderson has stated his desire to avoid a clash with Big Buck’s before the World Hurdle at the Festival, which would mean he is far more likely to take up this engagement rather than wait for the Long Walk at Ascot a week later.
David Pipe has entered Dynaste, a most impressive winner over the fixed brush hurdles at Haydock, and his novice chasing career has been delayed to see what heights he can reach over hurdles first.
Paul Nicholls has entered The Knoxs, owned by Graham Wylie, an impressive winner back over hurdles on his first start for the yard.
Donald McCain has entered Any Given Day, second to Karabak last season, and Drill Sergeant.
Sparky May, Get Me Out Of Here, Zanir, Cockney Trucker and The Jigsaw Man complete the entries.
The stanjames.com International Hurdle has been reopened as insufficient entries were received.
Meanwhile, Henrietta Knight has decided to let Somersby run in the Betfred Peterborough Chase at Huntingdon on Thursday.
After chasing home Master Minded in the Amlin 1965 Chase at Ascot, Knight had suggested her stable star could be heading straight for the King George at Kempton on Stephen’s Day.
But Knight, who has won the Peterborough Chase eight times, believes the Grade Two over an extended two and a half miles is the perfect race for the seven-year-old.
“It’s a race we’ve been very fortunate in. Hopefully it will set him up nicely for the King George,” said Knight.