Saquon Barkley leads Philadelphia Eagles to rout of New York Giants

Elsewhere, James Cook ran for 216 yards and two touchdowns as the Buffalo Bills hammered the Carolina Panthers.

Saquon Barkley and the Eagles got the better of the Giants. Picture: Matt Slocum/AP

Saquon Barkley scored two touchdowns as the Philadelphia Eagles beat divisional rivals the New York Giants 38-20.

However, the game was overshadowed by a serious-looking ankle injury suffered by Giants rookie Cam Skattebo.