Quigley, who was substituted in the 56th minute, bagged 2-6 for the Erne men.
After Leitrim opened the scoring with a Kevin Conlan point in the 10th minute Fermanagh set out on a demolition mission that saw them take a 1-8 to 0-3 lead by the interval, with Quigley flicking home his first goal just before the short whistle.
When Quigley struck for his second goal with 15 minutes to go he stretched Fermanagh’s lead to 2-13 to 0-4. Prior to that points to Fermanagh’s tally had been added by Shane McCabe, Paul Ward, Daryl Keenan, Quigley and Ryan Jones.
Scorers for Fermanagh: S Quigley 2-6 (3fs), D Kille, R Jones, D Keenan 0-2 each, E Donnelly, S McCabe, P Ward 0-1 each.
Scorers for Leitrim: E Mulligan 0-4 (3fs), K Conlan, W McKeon, S Moran 0-1 each.
FERMANAGH: R Gallagher; N McGovern, J Woods, M Jones; C Quigley, R McCluskey, B Mulrone; S Lyons, E Donnelly; D Keenan, S McCabe, B Óg Maguire; R Jones, D Kille, S Quigley.
Subs: D Kelly for Mulrone (ht), P Ward for Maguire (ht), M McGrath for McCabe (56), Sean Quigley for Seamus Quigley (56), P Cosgrove for Donnelly (60).
LEITRIM: C McCrann; J Glancy, K Egan, D Beck; C Clarke, F McMorrow, W McKeon; D Lowe, S Moran; P Brennan, R Lowe, C Ryan; K Conlan, P McGowan, E Mulligan.
Subs: D Sweeney for D Lowe (35), E Williams for Beck (35), R Cox for Conlan (46), G Hickey for R Lowe (58), C Sheridan for Brennan (67).
Referee: S. McLaughlin (Donegal).