Jamaican Blake, double Olympic silver medallist at London in the sprints, benefited from a false start by rival Tyson Gay — and the American’s subsequent disqualification — to win the 100 metres in a time of 9.76 seconds.
Compatriot Nesta Carter was a distant second in 9.95secs with Ryan Bailey of the United States third.
“I am not at all surprised that after the Olympics, I am coming out so strong and so fast. It’s because my coach has a plan for me,” said Blake of Glen Mills, who also coaches double Olympic sprint champion Bolt.
“Next year I can be even better. I am feeling good. And I am not surprised to run so fast in bad weather because I am the beast, bad weather cannot stop me.
“It’s a pity that Tyson Gay could not run with us, the race would have been even more competitive.”
Bolt, meanwhile was pushed hard by Jason Young in the 200m but eventually eased away over the last 50 metres to take the plaudits in a very respectable 19.66 seconds,.
Bolt jokingly made shivering gestures before leaving the opposition in his wake in familiar style.
“I’m happy to run a sub-20 time but I did not want to push my body,” said Bolt. “It is the end of the of the season and I have to be careful.”
In other events, Kenya’s David Rudisha, who set a new world record on his way to Olympic gold in London, was pipped to victory in the 800m by Ethiopia’s Mohammed Aman — who took the Diamond League series as a result.
Rudisha, assisted by a pacemaker, sped away on the first lap but clearly went too early as the pack caught up with him around 200 metres from the end and Aman passed him on the curve to win in one minute 42.53.
“My legs felt tired and I cannot run well if the weather is not good,” said 23-year-old Kenyan Rudisha, running in his only post-Olympic race of the year.
“I hoped for a fast race here and I’m a little disappointed... It was the rain which stopped me.”
Aman, sixth in London, said: “It was a difficult race but I was in good shape.”
Olympic champion Shelly-Ann Fraser-Pryce easily won the women’s 100m, beating Carmelita Jeter into second place after losing out to the American silver medallist in Lausanne and Birmingham.
Olympic champion Sanya Richards-Ross won the women’s 400 metres in 50.21 seconds ahead of Botswana’s Amantle Montsho.
Croatia’s Olympic gold medallist Sandra Perkovic won the women’s discus but Olympic long jump champion Brittney Reese retired injured in her event, saying she had aggravated a stress fracture in her left ankle.